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LASTREVIEWED 23.03.2017

Brand Name Kisqali
Generic Name ribociclib


Distributer Novartis Pharmaceuticals Corporation East Hanover, New Jersey 07936.Revised: Mar 2017.
    Pharmacotherapeutic group     Chemical name     Description     Pharmacokinetics     Clinical Pharmacology     Indications     ContraIndications     Warnings     Precautions     Side effects     Dosage and administration     Overdosage     Drug interactions     Patient Information     How Supplied     Storage conditions And Handling

Description

KISQALI® (ribociclib) is a kinase inhibitor.
Ribociclib succinate is a light yellow to yellowish brown crystalline powder.The molecular formula for ribociclib succinate is C23H30N8O·C4H6O4 and the molecular weight is 552.64 g/mol (Free base: 434.55 g/mol).
KISQALI film-coated tablets are supplied for oral use and contain 200 mg of ribociclib free base (equivalent to 254.40 mg ribociclib succinate).The tablets also contain colloidal silicon dioxide, crospovidone, hydroxypropylcellulose, magnesium stearate and microcrystalline cellulose.The film-coating contains iron oxide black, iron oxide red, lecithin (soya), polyvinyl alcohol (partially hydrolysed), talc, titanium dioxide, and xanthan gum as inactive ingredients.


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