Manufacturer Rottendorf Pharma GmbH 59320 Ennigerloh North Rhine-Westphalia Germany. Manufactured for: Veloxis Pharmaceuticals, Inc. 499 Thornall Street, 3rd floor, Edison, New Jersey 08837, United States
ENVARSUS XR, a calcineurin-inhibitor immunosuppressant,
is available for oral administration as extended-release tablets containing the
equivalent of 0.75 mg, 1 mg, or 4 mg of anhydrous tacrolimus USP.Inactive
ingredients include hypromellose USP, lactose monohydrate NF, polyethylene
glycol NF, poloxamer NF, magnesium stearate NF, tartaric acid NF, butylated
hydroxytoluene NF, and dimethicone NF. Tacrolimus is the active ingredient in ENVARSUS XR.
Tacrolimus is a macrolide immunosuppressant produced by Streptomyces
tsukubaensis.Chemically, tacrolimus is designated as [3S-[3R*[E(1S*,3S*,4S*)],
monohydrate. The chemical structure of tacrolimus is:
Tacrolimus has an empirical
formula of C44H69NO12•H2O and a
formula weight of 822.03.Tacrolimus appears as white crystals or crystalline
powder.It is practically insoluble in water, freely soluble in ethanol, and
very soluble in methanol and chloroform.
Sale provisoErrors found - 0